Accumulation of 5'-Inosinic Acid and 5'-Xanthylic Acid by Bacillus subtilis
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چکیده
منابع مشابه
5-bromouracil utilization by Bacillus subtilis.
The replacement of thymine (T) in deoxyribonucleic acid (DNA) by 5-bromouracil (BU) (F. Weygand, A. Wacker, and H. Dellweg, Z. Naturforsch. 7b:19, 1952) is an aid in density separation of types of DNA, and in studies on radiobiology and mutagenesis. The usefulness of BU is, however, limited by its toxic effects. Extensive substitution in DNA of T by BU is lethal for most Escherichia coli and Ba...
متن کاملProperties of 5-fluorouracil-containing ribonucleic acid and ribosomes from Bacillus subtilis.
Growth of a strain of Bacillus subtilis that requires uracil, thymine, adenine, and tryptophan in the presence of 5-fluorouracil (FU) results in the synthesis of ribonucleic acid (RNA) and ribosomes in which 55 to 65% of the RNA uracil has been replaced by the fluorine derivative. Examination of analogue-containing ribosomes by sucrose density gradient centrifugation and thermal denaturation st...
متن کاملElectrochemical Synthesis of 5-Aminosalicylic Acid from 5- Nitrosalicylic Acid in Alkaline Media
5-Aminosalicylic acid (5-ASA) is currently prepared by electrochemical reduction of 5-nitrosalicylic acid (5-NSA) in acidic media. In this work, electrolytic reduction of 5-NSA in alkaline media is presented. Reactionconditions and parameters such as anode and cathode electrodes, electrolyte type, reaction time, temperature,current, and the pH for isolation of product are investigated. The yiel...
متن کاملInosinic Acid Dehydrogenase Activity
ated in normal subjects and in patients with the LeschNyhan syndrome. A significant difference in activity was found between erythrocytes derived from normal controls (1.21±0.47 pmoles/hr per mg protein) and from 15 patients with the Lesch-Nyhan syndrome (6.72 ±6.23 pmoles/hr per mg protein). However, no difference in activity was demonstrable in muscle or leukocytes derived from normal and Les...
متن کامل5-Bromouracil-tolerant mutants of Bacillus subtilis.
5-Bromouracil (BU)-tolerant mutants of Bacillus subtilis 23 (thy his) have been isolated. Several classes of tolerant mutants were obtained by a sequential selection procedure. The classes can be distinguished by their relative BU tolerance as well as several other phenotypic characteristics. The mutants can grow for an extended period of time in minimal medium supplemented with amino acids and...
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ژورنال
عنوان ژورنال: Agricultural and Biological Chemistry
سال: 1972
ISSN: 0002-1369,1881-1280
DOI: 10.1271/bbb1961.36.227